I have no idea what is possible in this area, but I do know there are plenty of companies selling these devices and I don't know of any where interference with the usb 3 (and I believe cables running to them) aren't an issue. Not to mention that I often read about how they'll say certain stuff often won't work with them - like maybe a mouse.
I don't know if that latter part is because of the interference or if there is some other factor.
When I set up the dongle for the TextBlade on one USB 3.0 hub, it was a disaster. I ended up sending that one back. I have another which does work, but it took some finagling. The hub is plugged into the computer, then I have an extension (about 8 inches) that is plugged into the hub. At the end of that extension, I have a USB 2.0 (or maybe it is 1.0 - it isn't marked) hub. That hub has an extension while itself (3 inches). Into that small hub, I have my dongle from WayTools and also the receiver for my Logitech MX Performance Mouse.
The computer and USB 3.0 hub are both on the desk top (hub right at the front). The extensions then go down below the desktop which, possibly, blocks some interference? I haven't tested this for a very long time after I got it working.
Anyway, maybe @WayTools can see a way to make a hub that minimizes these issues - after general release of the TextBlade, of course. Computers don't have enough ports to suit me at all!